Ephrin-a1

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August undefined, 2024

WebThis Ephrin-A1 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Ephrin-A1 protein in Cell supernatant . It contains … WebEphrin A1 Antibodies. Antibodies that detect Ephrin A1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, …

ephrin-A1 siRNA (m), shRNA and Lentiviral Particle Gene Silencers ...

WebHigh expression of ephrin-A1 caused phosphorylation on Y588 in EphA2 and dephosphorylation on S897 in EphA2 in SCLC cell lines. In addition, SCLC cell lines developed chemoresistance, expression of ephrin-A1 was markedly reduced, and Akt-pS473 levels increased. The repression of EphA2-pS897 by ephrinA1 was alleviated … WebAnti-Ephrin-A1 (extracellular) Antibody (#AER-031) can be used in western blot and live cell imaging applications. The antibody recognizes an extracellular epitope and thus is ideal for detecting Ephrin-A1 in living … gsfc employees corner

Ephrin - Wikipedia

WebDec 31, 2024 · Eph (erythropoietin-producing hepatoma) receptors and Ephrin ligands constitute the largest subfamily of receptor tyrosine kinase (RTK), which were first discovered in tumors. Heretofore, Eph protein has been shown to be involved in various tumor biological behaviors including proliferation and progression. WebEphrin A1 Antibody (34-3300) in ICC/IF Immunofluorescent analysis of Ephrin-A1 was performed using 90% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. WebEphrin-A1 that is a membrane-anchored ligand for EphAs was co-localized with EphA1 and EphA2 in lung vascular endothelial cells. We recently uncovered the molecular … final mile delivery service houston

Ephrin A1 Polyclonal Antibody (34-3300) - thermofisher.com

人载脂蛋白A1（Apo-A1）抗体 ELISA试剂盒供应-智慧城市网

WebMay 13, 2024 · Ephrin-A1 / metabolism Exosomes* / metabolism Female Humans MicroRNAs* / metabolism Neovascularization, Pathologic / pathology Rats Receptor, EphA2 / metabolism* Signal Transduction / genetics Tumor Microenvironment Ephrin-A1 MicroRNAs Receptor, EphA2 AMP-Activated Protein Kinases WebMar 2, 2024 · Ephrin-A1 heralds a poor prognosis for CRC patients. Ieguchi K. et al. demonstrated in HEK293 cells that the ADAM-12-cleaved ephrin-A1 (ephrin-A1 174R) phosphorylated the EPHA2 and dephosphorylated Akt comparably with ephrin-A1-Fc while inducing defects in cells’ motility. In xenograft models, the treatment with KB-R7785, … final mile delivery service syracuseWebThere are two subfamilies of Ephrins, Ephrins-As (Ephrin-A1 to A10), and Ephrins-Bs (Ephrin-B1 to B6), binding to the tyrosine receptor kinases EphAs and EphBs, respectively. Ephrins-As have a GPI-anchor at their C-terminus. Ephrin-B … gsfc case study

"WebApr 12, 2024 · Blockade of Ephrin-A1/EphA2 signaling with EphA2-Fc chimeric receptors abrogates corneal angiogenesis in vivo . Evidence also suggests that Ephrin-A1 … " - Ephrin-a1

Ephrin-a1

WebRabbit polyclonal Ephrin A1 antibody. Validated in IHC and tested in Human. Immunogen corresponding to recombinant fragment. WebAug 18, 2024 · Eph receptors and the corresponding Eph receptor-interacting (ephrin) ligands jointly constitute a critical cell signaling network that has multiple functions. The tyrosine kinase EphA2, which belongs to the family of Eph receptors, is highly produced in tumor tissues, while found at relatively low … Targeting EphA2 in cancer

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WebJan 18, 2024 · Ephrin-A1, a ligand for the EphA receptors, was identified as an immediate early response gene to TNFα. 4 Ephrin-A1 is a plasma membrane protein anchored by glycosylphosphatidylinositol (GPI) although ephrin-A1 was originally identified as a soluble factor. 4 The EphA receptors transmit their downstream signals mediated by their … WebJan 21, 2016 · Ephrin-A:EphA forward signalling and ephrin-B1 reverse signalling are important for these short-distance, lateral migratory events, but the mechanism behind …

WebKnow comprehensive Ephrin-A1 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction. WebEphrin receptors (Ephs) are receptor tyrosine kinases (RTKs) implicated in tissue development and homeostasis, and they are aberrantly expressed in tumors. ... ephrin-A1–5, and five type B Ephs, EphB1–4 and EphB6, which interact with three type B ephrins, ephrin-B1–3. Eph–ephrin complexes emanate bidirectional signals that ultimately ...

WebEph signaling, which arises following stimulation by ephrins, is known to induce opposite cell behaviors such as promoting and inhibiting cell adhesion as well as promoting cell-cell adhesion and repulsion by altering the organization of the actin cytoskeleton and influencing the adhesion activities … Ephrin A1 is a protein that in humans is encoded by the EFNA1 gene. This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the … See more Model organisms have been used in the study of EFNA1 function. A conditional knockout mouse line, called Efna1 was generated as part of the International Knockout Mouse Consortium program—a high-throughput … See more • Pandey A, Lindberg RA, Dixit VM (Sep 1995). "Cell signalling. Receptor orphans find a family". Current Biology. 5 (9): 986–9. See more

WebMar 1, 2024 · ephrin-A1 Antibody (A-5) is a mouse monoclonal IgG 2b κ ephrin-A1 antibody, cited in 8 publications, provided at 200 µg/ml. specific for an epitope mapping between amino acids 151-176 at the C-terminus of ephrin-A1 of human origin. ephrin-A1 Antibody (A-5) is recommended for detection of ephrin-A1 of mouse, rat and human …

WebIn direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) Ephrin-A1 is observed and less than 1% cross-reactivity with recombinant mouse (rm) Ephrin-B1, rmEphrin-A5, rmEphrin-A4, rmEphrin-A2, and rmEphrin-B1 is observed. Source Polyclonal Goat IgG Purification Antigen Affinity-purified Immunogen final mile logistics meaningWebNov 1, 2006 · Ephrin-A1, the prototypic ligand for EphA receptor tyrosine kinases, is overexpressed in vascularized tumors relative to normal tissue. Moreover, ephrin-A1-Fc fusion proteins induce endothelial cell sprouting, migration, and assembly in vitro, and s.c. vascular remodeling in vivo. gsfc earth scienceWeb上海康朗生物科技有限公司主要致力于“Anti-Eph receptor A1抗体”的生产销售。多年的“Anti-Eph receptor A1抗体”生产与销售的经验，与各行业新老用户建立了稳定的合作关系，我公司经营的产品名称深受广大用户信赖。欢迎来电咨询或前来选购。联系电话：021-61998208。 final milestone art history 1WebOf the eight ephrins that have been identified in humans there are five known ephrin-A ligands (ephrin-A1-5) that interact with nine EphAs (EphA1-8 and EphA10) and three … gsfc dealershipWebSep 13, 2016 · Ephrin receptors (Ephs) are reported to control metastatic signaling of non-small cell lung cancer (NSCLC) and other tumors. Here we show for the first time that blocking expression of the Eph ligand Ephrin B3 inhibits NSCLC cell migration and invasion. We demonstrate that Ephrin B3 directly binds the EphAs EphA2, EphA3, EphA4, and … gsfc core hoursWebMar 1, 2024 · ephrin-A1 Antibody (A-5) is a mouse monoclonal IgG 2b κ ephrin-A1 antibody, cited in 8 publications, provided at 200 µg/ml. specific for an epitope mapping … gsfc customer serviceWebEphrin-A1: Products. There are two structural groups of ephrin ligands which bind to a family of receptor tyrosine kinases (Eph). A-type ephrins bind A-type receptors, which … gsfc flight projects directorate