WebDec 13, 2011 · Fish SOCS genes are broadly expressed and also show species-specific expression patterns. They can be upregulated by cytokines, such as IFN-γ, TNF-α, IL-1β, IL-6, and IL-21, by immune stimulants such as LPS, poly I:C, and PMA, as well as by viral, bacterial, and parasitic infections in member- and species-dependent manners. WebNov 1, 2024 · A recent human clinical trial NCT04426669, NCT03538613 [1, 2] evidenced the success of targeting CISH/SOCS-1 in NK-cells [3,4], T-cells [5,6], and DCs [7] in further strengthening the efficacy of ...

Identification of SOCS5 Gene in the Chinese Giant Salamander

WebThe protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein … WebThrough whole and lineage specific genome duplication events, the teleost cytokine/SOCS network is complex. Not only are the orthologues of all mammalian SOCS members present, namely cytokine inducible Src homology 2 (SH2)-containing protein (CISH) and SOCS-1 to -7, but multiple gene copies exist that may potentially become functionally divergent. readlines documentation python

鲤鱼CISH基因克隆鉴定与组织特异性表达分析

WebCreate 1-Month free SSH account, VPN server, V2ray account, Proxy and PPTP server Singapore, Indonesia, Turkey, Thailand, Iran, India, UAE, US, UK, Brazil, Germany, … WebNov 16, 2012 · These findings suggest that high levels of CISH/SOCS inhibitors represent a novel aspect of a leukemia-specific gene expression pattern. Importantly, we found that high expression levels of SOCS2 ... WebNov 16, 2012 · SOCS (suppressors of cytokine signaling) are a family of intracellular proteins, including SOCS1–7 and CISH (cytokine induced SH2 domain protein). They … readline while loop